Family

Spermidine/spermine synthase, eukaryotes (IPR030668)

Short name: Spermi_synthase_euk

Family relationships

Description

The ubiquitous polyamines spermidine and spermine are involved in numerous cellular functions and they are essential for cell growth and proliferation. Spermidine synthase (EC:2.5.1.16) (putrescine aminopropyltransferase) catalyses the last step in the biosynthesis of spermidine from arginine and methionine; the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor [PMID: 17585781]. Spermine synthase (EC:2.5.1.22) (spermidine aminopropyltransferase) converts spermidine into spermine using decarboxylated S-adenosylmethionine as the cofactor [PMID: 19859664].

This entry consists of spermidine and spermine synthases from eukaryotes.

GO terms

Biological Process

GO:0006595 polyamine metabolic process

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF