tRNA isopentenyltransferase, eukaryotes (IPR030666)

Short name: IPP_transferase_euk

Overlapping homologous superfamilies


Family relationships

  • IPP transferase (IPR018022)
    • tRNA isopentenyltransferase, eukaryotes (IPR030666)


The N(6)-(isopentenyl)adenosine (i(6)A) modification of some tRNAs at position A37 is found in all kingdoms and facilitates codon-specific mRNA decoding, but occurs in different subsets of tRNAs in different species [PMID: 21873461]. This entry represents tRNA isopentenyltransferase from eukaryotes. It catalyses the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A) [PMID: 11111046].

GO terms

Biological Process

GO:0008033 tRNA processing

Molecular Function

GO:0005524 ATP binding
GO:0052381 tRNA dimethylallyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.