Synemin (IPR030634)

Short name: SYNM

Overlapping homologous superfamilies


Family relationships


Synemin, also known as desmuslin, is a type-VI intermediate filament (IF) protein which plays an important cytoskeletal role within the muscle cell cytoskeleton [PMID: 11353857]. It associates with the major IF proteins, desmin and/or vimentin, within muscle cells and forms heteropolymeric IFs [PMID: 18028034].

GO terms

Biological Process

GO:0045104 intermediate filament cytoskeleton organization

Molecular Function

GO:0005200 structural constituent of cytoskeleton
GO:0008307 structural constituent of muscle

Cellular Component

GO:0005882 intermediate filament

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.