Rho guanine nucleotide exchange factor 10 (IPR030632)

Short name: ARHGEF10

Overlapping homologous superfamilies


Family relationships


ARHGEF10 is a Rho guanine nucleotide exchange factor that may play a role in developmental myelination of peripheral nerves [PMID: 14508709]. It was found to regulate mitotic spindle formation and play a role in the regulation of the cell division cycle [PMID: 19635168].

GO terms

Biological Process

GO:0090307 mitotic spindle assembly
GO:0022011 myelination in peripheral nervous system
GO:0035023 regulation of Rho protein signal transduction

Molecular Function

GO:0005089 Rho guanyl-nucleotide exchange factor activity

Cellular Component

GO:0005813 centrosome
GO:0005829 cytosol

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.