Purine-rich element-binding protein beta (IPR030499)

Short name: PURbeta

Overlapping homologous superfamilies


Family relationships


PURbeta belongs to the purine-rich element binding (PUR) protein family, which consists of PURalpha, PURbeta and PURgamma. PURalpha and PURbeta are DNA-binding proteins that play a role in cell growth and differentiation by modulating both transcriptional and translational controls of gene expression [PMID: 17612644]. They are linked to the repression of genes such as smooth muscle alpha-actin (SMalphaA), alpha-myosin heavy chain, and beta-myosin heavy chain [PMID: 12933792, PMID: 19496623].

GO terms

Biological Process

GO:0030154 cell differentiation
GO:0008283 cell proliferation
GO:0045892 negative regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.