Centrosomal protein of 131kDa (IPR030465)

Short name: CEP131

Overlapping homologous superfamilies


Family relationships



Centrosomal protein of 131kDa (CEP131) is a cilium-specific protein required for cilium/flagellum formation [PMID: 21750193]. In Drosophila, CEP131, also known as Azi1, functions in ciliogenesis and is involved in genome stability and centriole duplication [PMID: 22797915, PMID: 24415959]. In mice, it mediates trafficking events necessary for spermiogenesis and male fertility [PMID: 24415959]. It interacts with BBS4 (Bardet-Biedl syndrome 4) and regulates ciliary trafficking of the BBSome [PMID: 24550735].

GO terms

Biological Process

GO:0035735 intraciliary transport involved in cilium assembly

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.