Active Site

Glycosyl hydrolases family 31, active site (IPR030458)

Short name: Glyco_hydro_31_AS

Description

Glycoside hydrolase family 31 GH31 comprises enzymes with several known activities; alpha-glucosidase (EC:3.2.1.20), alpha-galactosidase (EC:3.2.1.22); glucoamylase (EC:3.2.1.3), sucrase-isomaltase (EC:3.2.1.48); isomaltase (EC:3.2.1.10); alpha-xylosidase (EC:3.2.1); alpha-glucan lyase (EC:4.2.2.13).

Glycoside hydrolase family 31 groups a number of glycosyl hydrolases on the basis of sequence similarities [PMID: 1747104, PMID: 1761061, PMID: 1743281]. An aspartic acid has been implicated [PMID: 1856189] in the catalytic activity of sucrase, isomaltase, and lysosomal alpha-glucosidase.

The region around this active residue is highly conserved and is represented in this entry.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns