Family

Membrane-spanning 4-domains subfamily A member 3 (IPR030419)

Short name: MS4A3

Overlapping homologous superfamilies

None.

Family relationships

Description

Membrane-spanning 4-domains subfamily A member 3 (MS4A3), also known as HTm4, is an hematopoietic modulator for the G1-S cell cycle transition [PMID: 11781350]. HTm4 binds to the Cdk-associated Phosphatase (KAP)-Cdk2-Cyclin A complex, triggering the dissociation of cyclin A and facilitating dephosphorylation of Cdk2 by KAP [PMID: 15671017, PMID: 19818099].

GO terms

Biological Process

GO:0051726 regulation of cell cycle

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER