Family

Transcription factor hamlet (IPR030413)

Short name: Ham

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Protein Hamlet (Ham) is a key target of the SWI/SNF complex (a nucleosome remodeling complex) in Drosophila [PMID: 24630726]. It has critical roles in cell fate decisions in external sensory organs and the olfactory system [PMID: 12193790, PMID: 15075290, PMID: 22197833]. Hamlet is the Drosophila homologue of Prdm3/Evi1 and Prdm16, two mammalian proteins that can act as proto-oncogenes and tumour suppressors [PMID: 22028065, PMID: 22669819].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER