Probable phospholipid-transporting ATPase VB (IPR030359)

Short name: ATP10B

Overlapping homologous superfamilies


Family relationships


Probable phospholipid-transporting ATPase VB (also known as ATP10B) belongs to the IV subfamily of the P-type ATPases (P4-ATPase) family. P4-ATPases are phospholipid flippases that translocate phospholipids from the exoplasmic (lumenal) to the cytoplasmic leaflet of cellular membranes. ATP10C requires CDC50A for its exit from the endoplasmic reticulum (ER) and final subcellular localisation [PMID: 21914794]. The function of ATP10B is not clear.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.