Fatty acid transport protein 5 (IPR030302)
Short name: FATP5
Fatty acid transport protein 5 (FATP5; also known as bile acyl-CoA synthetase) belongs to the FATP family, whose members facilitate long- and very long-chain fatty acid uptake [PMID: 23271751, PMID: 15469937]. FATP5 is a bifunctional protein required for both hepatic fatty acid uptake and bile acid reconjugation [PMID: 17495600]. It has bile acid-CoA ligase activity. Fatp5 knockout mice exhibit lower levels of hepatic triglycerides and free fatty acids due to decreased liver fatty acid uptake [PMID: 18524776].
GO:0006699 bile acid biosynthetic process
GO:0016021 integral component of membrane
- PTHR43107:SF4 (PTHR43107:SF4)