Sodium/potassium/calcium exchanger 5 (IPR030245)

Short name: SLC24A5

Overlapping homologous superfamilies


Family relationships


Sodium/potassium/calcium exchanger 5 (NCKX5), also known as SLC24A5, is a potassium-dependent sodium-calcium exchanger found at the trans-Golgi network of melanocytes. It is involved in pigmentation [PMID: 16357253, PMID: 18166528, PMID: 16357234, PMID: 23224873].

GO terms

Biological Process

GO:0006811 ion transport
GO:0048021 regulation of melanin biosynthetic process

Molecular Function

GO:0008273 calcium, potassium:sodium antiporter activity

Cellular Component

GO:0016021 integral component of membrane
GO:0005802 trans-Golgi network

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.