GPN-loop GTPase 1 (IPR030230)

Short name: Gpn1/Npa3/XAB1

Overlapping homologous superfamilies

Family relationships


GPN-loop GTPase 1 (Gpn1) belongs to the GPN-loop GTPase family [PMID: 17468740]. It is also known as Npa3 in budding yeasts and XAB1 in humans.

Npa3 has GTPase activity that is essential for its binding to RNA polymerase II (RNAPII) and the nuclear localisation of RNAPII [PMID: 21844196].

XAB1 is a cytoplasmic GTPase involved in nuclear localisation of DNA repair protein XPA [PMID: 11058119].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003924 GTPase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.