Solute carrier family 10 member 1 (IPR030208)

Short name: SLC10A1

Overlapping homologous superfamilies

Family relationships


Solute carrier family 10 member 1 (SLC10A1), also known as sodium/taurocholate cotransporting polypeptide (NTCP), represents a hepatic sodium/bile acid uptake system that exhibits broad substrate specificity [PMID: 8132774]. NTCP also transports various non-bile acid organic compounds, including steroidal hormones such as estrone-3-sulfate and dehydroepiandrosterone (DHEAS), bromosulphthalein and a variety of xenobiotics [PMID: 21103971]. It also mediates transport of (sulfated) iodothyronines [PMID: 19682536].

GO terms

Biological Process

GO:0015721 bile acid and bile salt transport

Molecular Function

GO:0008508 bile acid:sodium symporter activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.