Family

Potassium voltage-gated channel subfamily H member 6 (IPR030172)

Short name: KCNH6

Family relationships

Description

Potassium voltage-gated channel subfamily H member 6 (KCNH6), also known as ether-a-go-go-related gene (ERG, ERG2), has a key role in the control of cardiac action potential repolarisation [PMID: 16554806, PMID: 22742967]. It is a pore-forming (alpha) subunit of voltage-gated potassium channel. In human, mutations in ERG can cause congenital long QT syndrome, a disorder of cardiac repolarisation [PMID: 19027781].

GO terms

Biological Process

GO:0006813 potassium ion transport

Molecular Function

GO:0005249 voltage-gated potassium channel activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER