Actin-related protein 2/3 complex subunit 1A (IPR030140)

Short name: ARC1A

Overlapping homologous superfamilies

Family relationships


The Arp2/3 complex binds to pre-existing actin filaments and nucleates new daughter filaments, and thus becomes incorporated into the dynamic actin network at the leading edge of motile cells and other actin-based protrusive structures [PMID: 9600938].

The human Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. This entry represents actin-related protein 2/3 complex subunit 1A (ARC1A) from vertebrates. ARC1A shares protein sequence similarity with ARPC1B and is predicted to function as ARPC1B in the Arp2/3 complex.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.