F-BAR domain only protein 1 (IPR030121)

Short name: FCHo1

Overlapping homologous superfamilies


Family relationships



F-BAR domain only protein 1 (FCHo1) belongs to the F-BAR family, whose members have been implicated in cell membrane processes such as membrane invagination, tubulation and endocytosis [PMID: 23384583]. FCHo1 functions in an early step of clathrin-mediated endocytosis. It has a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits [PMID: 20448150].

GO terms

Biological Process

GO:0072583 clathrin-dependent endocytosis

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.