Melanoma-associated antigen 4/5 (IPR030098)

Short name: MAGEA4/MAGEA5

Overlapping homologous superfamilies


Family relationships


Proteins in this group consist of melanoma-associated antigens 4 and 5, which belong to the MAGE family of genes that are active in various types of tumors and silent in normal tissues except in testis and placenta [PMID: 7927540, PMID: 21933694]. Expression of proteins in this family may suppress apoptosis by suppressing p53 [PMID: 17942928].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.