Family

Melanoma-associated antigen 3/6 (IPR030097)

Short name: MAGEA3/MAGEA6

Family relationships

None.

Description

Proteins in this group consist of melanoma-associated antigens 3 and 6, which belong to the MAGE family of genes that are active in various types of tumors and silent in normal tissues except in testis and placenta [PMID: 7927540, PMID: 21933694]. Expression of proteins in this family may suppress apoptosis by suppressing p53 [PMID: 17942928].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER