Family

SWI/SNF complex subunit BAF57 (IPR030089)

Short name: BAF57

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

BAF57 (also known as SMARCE1) is a subunit of the SWI/SNF complex, which is an ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling. In response to hormone, BAF57 facilitates the recruitment of SWI/SNF to the nuclear receptors at target promoters/enhancers to regulate transcription [PMID: 20460533]. BAF57 is also required for maintaining the subunit composition of the SWI/SNF complex. It plays an important role in cell cycle progression through the transcriptional regulation of a subset of cell cycle-related genes [PMID: 20460533].

GO terms

Biological Process

GO:0043044 ATP-dependent chromatin remodeling

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016514 SWI/SNF complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER