Lysozyme-like protein 3 (IPR030058)

Short name: LYZL3

Overlapping homologous superfamilies

Family relationships


The vertebrate lysozyme family is composed of lysozyme c, lactalbumin and calcium-binding lysozyme. The classical lysozyme c has been extensively studied [PMID: 21676251]. From human testis cDNA libraries, a group of lysozyme c-like sequences is identified [PMID: 21676251, PMID: 24013621]. The function of this group of lysozyme c-like proteins is not clear. Some of them (LYZL2, SLLP1/SPACA3/LYXL3, LYZL4 and LYZL6) are expressed in the male reproductive tract [PMID: 12606493, PMID: 16014814] and may be involved in fertilisation.

Lysozyme-like protein 3 (LYZL3), also known as sperm acrosome membrane-associated protein 3 (SPACA3/SLLP1/LYXL3), is one of them. Mouse LYZL3 (SLLP1) has been shown to be involved in sperm-egg binding and fertilisation [PMID: 15982649].

GO terms

Biological Process

GO:0009566 fertilization

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.