Pathways & interactions
Actin-related protein 6 (IPR030054)
Short name: Arp6
Overlapping homologous superfamilies
- Actin family (IPR004000)
- Actin-related protein 6 (IPR030054)
The actin family consists of conventional actin and actin-related proteins (ARPs). ARPs are predominantly localised in the nucleus, where they are involved not only in chromatin remodeling, but also affect the spatial organisation of the nucleus [PMID: 21647298].
Actin-related protein 6 (Arp6) is a nuclear actin-related protein conserved from yeast to vertebrates. Vertebrate Arp6 interacts with heterochromatin protein 1 (HP1). Yeast Arp6 is involved in telomere silencing, while Drosophila Arp6 is localised in the pericentric heterochromatin [PMID: 16487625].
- PTHR11937:SF47 (PTHR11937:SF47)