Actin-related protein 6 (IPR030054)

Short name: Arp6

Overlapping homologous superfamilies


Family relationships

  • Actin family (IPR004000)
    • Actin-related protein 6 (IPR030054)


The actin family consists of conventional actin and actin-related proteins (ARPs). ARPs are predominantly localised in the nucleus, where they are involved not only in chromatin remodeling, but also affect the spatial organisation of the nucleus [PMID: 21647298].

Actin-related protein 6 (Arp6) is a nuclear actin-related protein conserved from yeast to vertebrates. Vertebrate Arp6 interacts with heterochromatin protein 1 (HP1). Yeast Arp6 is involved in telomere silencing, while Drosophila Arp6 is localised in the pericentric heterochromatin [PMID: 16487625].

GO terms

Biological Process

GO:0006338 chromatin remodeling

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.