Neuroligin-2 (IPR030023)

Short name: NLGN2

Overlapping homologous superfamilies

Family relationships


Neuroligin-2 (NLGN2) belongs to the neuroligins (NLGNs) family, whose members interact with the neurexin family members and are involved in the modulation of synaptic transmission [PMID: 24860089]. NLGN2 is a postsynaptic cell adhesion protein that is predominantly expressed at inhibitory synapses and required for synapse specification and stabilisation [PMID: 23451101]. Its structure has been solved [PMID: 18250328].

GO terms

Biological Process

GO:0007155 cell adhesion
GO:0050804 modulation of chemical synaptic transmission
GO:0050808 synapse organization

Molecular Function

GO:0042043 neurexin family protein binding

Cellular Component

GO:0060077 inhibitory synapse
GO:0005887 integral component of plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.