Pathways & interactions
Short name: Villin
Overlapping homologous superfamilies
- Villin/Gelsolin (IPR007122)
- Villin (IPR030007)
Villin belongs to the villin/gelsolin family, whose members are actin-modulating proteins that sever F-actin, cap the barbed ends of actin filaments preventing monomer exchange, and promote the nucleation step of actin polymerisation [PMID: 17182858]. Villin is involved in actin remodelling necessary for many cellular processes requiring the actin cytoskeleton plasticity [PMID: 12181160, PMID: 18307996].
This entry represents villin from vertebrates.
No terms assigned in this category.
- PTHR11977:SF35 (PTHR11977:SF35)