Family

FERM and PDZ domain-containing protein 2 (IPR029906)

Short name: FRMPD2

Family relationships

None.

Description

FERM and PDZ domain-containing protein 2 (FRMPD2) may play a role in the regulation of tight junction formation [PMID: 19706687]. It interacts with NOD2 (nucleotide-binding oligomerisation domain-2) via leucine-rich repeats, and acts as a membrane-scaffolding complex that provides a spatial control mechanism for NOD2-mediated immune responses [PMID: 23213202].

GO terms

Biological Process

GO:0070830 bicellular tight junction assembly

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER