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Overview
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Domain architectures
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Structures
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Cross-references
ORM1-like protein 3 (IPR029883)
Short name: ORML3
Overlapping homologous superfamilies
None.
Family relationships
- ORMDL family (IPR007203)
- ORM1-like protein 3 (IPR029883)
Description
ORM1-like protein 3 (ORML3) is involved in the processes of endoplasmic reticulum stress induction [PMID: 19819884], sphingolipid regulation [PMID: 20182505, PMID: 23066021] and T-lymphocyte activation [PMID: 23100328]. ORMDL3 has been associated with the development of asthma [PMID: 24204796].
GO terms
Biological Process
GO:0090156 cellular sphingolipid homeostasis
GO:0006672 ceramide metabolic process
Molecular Function
No terms assigned in this category.
Cellular Component
GO:0005789 endoplasmic reticulum membrane
Contributing signatures
- PTHR12665:SF11 (PTHR12665:SF11)