Pathways & interactions
Short name: Rabaptin-5beta
Overlapping homologous superfamilies
- Rabaptin (IPR003914)
- Rabaptin-5beta (IPR029882)
Rabaptins interact with the GTP form of the small GTPase Rab5, a potent regulator of endocytic transport [PMID: 8521472]. Two Rabaptins have been identified, Rabaptin-5 and Rabaptin-5beta. Both proteins bind to Rab5 and cooperate in endocytic membrane fusion [PMID: 9524116].
This entry represents Rabaptin-5beta, which forms a complex with Rabex-5 to activate Rab5 (a small GTPase) and promote early endosomal fusion in endocytosis [PMID: 9524116].
- PTHR31179:SF6 (PTHR31179:SF6)