Family

Filamin-B (IPR029874)

Short name: FLNB

Family relationships

None.

Description

Filamin family consists of Filamin-A (FLN-A), Filamin-B (FLN-B) and Filamin-C (FLN-C). They are a group of actin binding proteins that may be involved in actin microfilaments organisation [PMID: 15516996].

This entry represents filamin B, which transduces signals from various membrane receptors and intracellular proteins onto the actin cytoskeleton [PMID: 24760772]. In humans it regulates chondrocyte proliferation and differentiation through Cdk1 signalling [PMID: 24551245].

This entry also includes gelation factor (actin-binding protein 120 or abpC) from the slime mould Dictyostelium discoideum.

GO terms

Biological Process

GO:0030036 actin cytoskeleton organization
GO:0030154 cell differentiation

Molecular Function

GO:0003779 actin binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER