Steroidogenic acute regulatory protein (IPR029866)

Short name: StAR

Family relationships


Steroidogenic acute regulatory protein (StAR) facilitates the biosynthesis of steroid hormones by regulating the transfer of cholesterol from the outer to the inner mitochondrial membrane [PMID: 24945345]. Mitochondrial fusion and ERK phosphorylation can direct StAR to the outer mitochondrial membrane to achieve a large number of steroid molecules per unit of StAR [PMID: 24945345, PMID: 18197253].

GO terms

Biological Process

GO:0006694 steroid biosynthetic process

Molecular Function

GO:0015485 cholesterol binding
GO:0017127 cholesterol transporter activity

Cellular Component

GO:0005739 mitochondrion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.