V-set and immunoglobulin domain-containing protein 1 (IPR029861)

Short name: VSIG1

Overlapping homologous superfamilies


Family relationships


V-set and immunoglobulin domain-containing protein 1 (VSIG1, also konwn as A34) belongs to the immunoglobulin superfamily (IgSF), whose members have one or more Ig-like domains in the extracellular region that is implicated in cell-cell adhesion, a transmembrane domain, and one cytoplasmic C-terminal region [PMID: 21991385]. VSIG1 is required for the proper differentiation of glandular gastric epithelia [PMID: 21991385].

GO terms

Biological Process

GO:0003382 epithelial cell morphogenesis
GO:0030277 maintenance of gastrointestinal epithelium

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.