Family

Protein AMBP (IPR029856)

Short name: AMBP

Family relationships

Description

Protein AMBP is a precursor that gives rise to two different secreted proteins upon endopeptidase cleavage in hepatocytes [PMID: 12204273]. One of the two proteins after cleavage, alpha1-microglobulin is a glycoprotein that belongs to the lipocalin family. It has immunoregulatory properties and is involved in heme-catabolism [PMID: 6171029, PMID: 11877257]. The second protein, bikunin, is a Kunitz-type proteinase inhibitor of the inter-alpha-inhibitor family [PMID: 8670091].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER