D site-binding protein (IPR029830)

Short name: DBP

Overlapping homologous superfamilies


Family relationships



D site-binding protein (DBP) belongs to the PAR (Proline and Acidic amino acid-Rich basic leucine ZIPper) transcription factor family, which consists of HLF, DBP and TEF proteins [PMID: 8786133]. DBP may bind DNA specifically as a homodimer or as a heterodimer with other PAR factors. It accumulates in the liver according to a very strong circadian rhythm regulated by hormones [PMID: 1297647].

GO terms

Biological Process

GO:0007623 circadian rhythm
GO:0006357 regulation of transcription by RNA polymerase II

Molecular Function

GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.