cAMP-dependent transcription factor ATF-3 (IPR029812)

Short name: ATF3

Overlapping homologous superfamilies


Family relationships


ATF3 belongs to the ATF/cAMP-response element-binding protein family. It is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It serves as a hub in cellular adaptive-response and plays important roles in cancer and immunity [PMID: 21061913, PMID: 21266251].

GO terms

Biological Process

GO:0006357 regulation of transcription by RNA polymerase II

Molecular Function

GO:0003700 DNA-binding transcription factor activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.