Proton pump-interactor (IPR029669)

Short name: PPI

Overlapping homologous superfamilies


Family relationships



This entry represents a group of plant proton pump-interactors, which may regulate plasma membrane ATPase activity. In Arabidopsis, proton pump-interactor 1 (PPI1, At4g27500) interacts with the C-terminal autoinhibitory domain of the membrane (PM) H(+)-ATPase [PMID: 16279950]. It promotes plasma membrane ATPase (AHA1 isoform) activity by binding to a site different from the 14-3-3 binding site [PMID: 16279950]. It is localised at the endoplasmic reticulum, from which it might be recruited to the plasma membrane [PMID: 19796364].

GO terms

Biological Process

GO:0010155 regulation of proton transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.