Ras guanyl-releasing protein 3 (IPR029645)

Short name: RASGRP3

Family relationships



Guanine nucleotide exchange factors (GEFs) couple extracellular stimuli to Ras protein activation [PMID: 10934204]. Ras guanyl-releasing protein 3 (RasGRP3) is an activator for H-Ras, R-Ras and Ras-associated protein-1/2 [PMID: 21602881]. Its expression has been linked to several cancers [PMID: 21602881, PMID: 24779681, PMID: 20876802].

GO terms

Biological Process

GO:0007265 Ras protein signal transduction
GO:0043087 regulation of GTPase activity

Molecular Function

GO:0005096 GTPase activator activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.