Myeloperoxidase (IPR029609)

Short name: MPO

Overlapping homologous superfamilies

Family relationships


Myeloperoxidase is a heme-containing glycosylated oxidoreductase that plays an important role in the microbicidal activity of phagocytes [PMID: 15689384]. It catalyses the production of hypochlorous acid (HOCl) in the presence of hydrogen peroxide (H2O2) and chloride anions [PMID: 20332087]. It is structurally related to eosinophil peroxidase (EPX/EPO) [PMID: 24802755].

GO terms

Biological Process

GO:0006952 defense response
GO:0002149 hypochlorous acid biosynthetic process

Molecular Function

GO:0004601 peroxidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.