Transient receptor potential cation channel subfamily M member 3 (IPR029583)
Short name: TRPM3
Overlapping homologous superfamilies
The TRPM subfamily of mammalian TRP channels includes TRPM3, which is a calcium-permeable nonselective cation channel [PMID: 24006495]. TRPM3 is expressed by a variety of cells, including nociceptive neurons, pancreatic beta cells, and vascular smooth muscle cells [PMID: 24756716]. TRPM3 channels are temperature sensitive and have been implicated in sensing noxious heat [PMID: 24006495, PMID: 24756716]. They may also play a role of TRPM3 in renal Ca2+ homeostasis [PMID: 12672799].
GO:0005227 calcium activated cation channel activity
GO:0016021 integral component of membrane
- PTHR13800:SF7 (PTHR13800:SF7)