Domain

ECSIT, C-terminal domain (IPR029342)

Short name: ECIST_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the C-terminal domain of the evolutionarily conserved signalling intermediate in Toll pathway (ECSIT) protein, an adapter protein of the Toll/IL-1 receptor signalling pathway, which is involved in the activation of NF-kappa-B via MAP3K1 [PMID: 10465784]. This domain is missing in isoform 2. This domain may be distantly homologous to the pleckstrin homology domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam