Domain

PEHE domain (IPR029332)

Short name: PEHE_dom

Domain relationships

None.

Description

This domain was first identified in drosophila MSL1 (male-specific lethal 1) [PMID: 12698291]. In drosophila it binds to the histone acetyltransferase males-absent on the first protein (MOF) and to protein male-specific lethal-3 (MSL3) [PMID: 15141166, PMID: 21217699]. This domain can also be found in KAT8 regulatory NSL complex subunit 1 (KANSL1 or NSL1), which is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription [PMID: 20018852].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam