Domain

RFX5, C-terminal (IPR029298)

Short name: RFX5_C

Domain relationships

None.

Description

Transcription of all the members of MHCII family of genes is controlled by a set of conserved transcription factors and promoter elements. One of these class II transactivators is the DNA-binding RFX complex, which consists of subunits RFX5 and its accessory proteins RFXAP and RFXANK [PMID: 10779326].

This entry represents the C-terminal domain of RFX5. The C-terminal domain mediates cooperative binding between the RFX complex and NF-Y, a transcription factor binding to the Y box sequence of MHC-II promoters [PMID: 10779326].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam