Cdc42 effector (IPR029273)

Short name: Cdc42_effect

Overlapping homologous superfamilies


Family relationships


The Rho-type GTPase Cdc42 regulates cell morphology and signal transduction in eukaryotic cells. The Cdc42 effector (CEP) or binder of Rho GTPase (BORG) proteins are involved in the organisation of the actin cytoskeleton [PMID: 11035016]. They may function as negative regulators of Rho GTPase signaling [PMID: 10490598].

This family consists of Cdc42 effector proteins, including CEP1-5 from humans.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.