Domain

ARF7 effector protein, C-terminal (IPR029264)

Short name: ARF7EP_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This domain represents the C terminus of the ARF7 effector protein (ARF7EP), also known as ARL14 effector protein. ARF7EP interacts with actin based motor protein myosin 1E (MYO1E) and may be involved in connecting MHC class II-containing cytoplasmic vesicles to the actin network in dendritic cells [PMID: 21458045]. It contains a conserved CXCXXXXCXXCXXXCXXCXXXXCXXXCXC motif in its C-terminal half.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam