Family

MORF4 family-associated protein 1 (IPR029254)

Short name: MRFAP1

Family relationships

None.

Description

MRFAP1 (MORF4 family-associated protein 1) and its interaction partner MORF4L1 (or MRG15) are target proteins of the NEDD8-cullin pathway, which plays an important role in the degradation of cell cycle regulators and transcriptional control networks. It has been suggest that MRFAP1 competes with MRGBP for binding to MORF4L1, thereby regulating MORF4L1 function in chromatin modification [PMID: 22038470].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER