Thymic stromal lymphopoietin (IPR029189)

Short name: TSLP

Overlapping homologous superfamilies

Family relationships



Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells [PMID: 11418668]. TSLP has proliferative effects on the myeloid cell line [PMID: 11480573] and may initiate asthma or atopic dermatitis responses by directly activating mast cells [PMID: 17242164].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005125 cytokine activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.