Domain

Acid ceramidase, N-terminal (IPR029130)

Short name: Acid_ceramidase_N

Domain relationships

None.

Description

This entry represents the N-terminal domain of acid ceramidase (AC), which degrades ceramide into sphingosine and fatty acid [PMID: 10610716], and N-acylethanolamine-hydrolysing acid amidase (NAAA). NAAA is an N-acylethanolamine-hydrolysing enzyme that shows structural and functional similarity to acid ceramidase [PMID: 15655246]. AC and NAAA can be cleaved into two chains: alpha and beta [PMID: 18281275, PMID: 17980170]. This entry represent the beta subunit (chain).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam