Domain

Splicing factor RBM39, linker (IPR029123)

Short name: RBM39_linker

Domain relationships

None.

Description

This entry represents a conserved linker between the second and the third RRM domain in human RBM39 (also known as CAPER) protein and other RNA splicing proteins. CAPER is a transcriptional coactivator of activating protein-1 (AP-1) and estrogen receptors (ERs). This linker was implicated in interactions with ERalpha and ERbeta [PMID: 11704680]. Preliminary results from JCSG suggest that this is a structured domain with a well defined fold.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam