Homologous Superfamily

CDC48 domain 2-like superfamily (IPR029067)

Short name: CDC48_domain_2-like_sf

Overlapping entries


This superfamily represents the CDC48 domain 2-like domain, which can be found in the N-terminal of the peroxisome biogenesis factor 1 and the domain 2 of the AAA ATPases.

CDC48 from yeasts is an AAA ATPase that is involved in protein export from the endoplasmic reticulum to the cytoplasm [PMID: 11740563].

Peroxisome biogenesis factor 1, also known as peroxin-1 or PEX1, is a component of the peroxisomal protein import machinery. In addition to its role in import, PEX1 together with PEX6, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol [PMID: 15634331, PMID: 16007078, PMID: 16911527].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.