Domain

Alpha/beta knot methyltransferases (IPR029028)

Short name: Alpha/beta_knot_MTases

Domain relationships

Description

This entry represents a alpha/beta knot structural domain that can be found in many RNA methyltransferases, including members from the SPOUT superfamily, EMG1/NEP1 methyltransferases and SAM-dependent RNA methyltransferases. The alpha/beta knot structure is extremely rare in protein structures as it poses a folding problem [PMID: 12596263].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY