Homologous Superfamily

Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily (IPR028978)

Short name: Chorismate_lyase_/UTRA_dom_sf

Overlapping entries


This superfamily represents a domain found in chorismate pyruvate-lyases, which catalyses the first step in ubiquinone synthesis, the removal of pyruvate from chorismate, to yield 4-hydroxybenzoate in Escherichia coli and other Gram-negative bacteria [PMID: 1644758]. The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine [PMID: 11583838], however this enzyme is found only in bacteria. Its activity does not require metal cofactors [PMID: 8012607].

GntR/HutC-type transcriptional regulators also contain this domain, such as FrlR [PMID: 21398478], TreR (trehalose operon transcriptional repressor) and PhnF [PMID: 16672238].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.