Molybdopterin synthase sulfur carrier subunit (IPR028887)

Short name: MOCS2A

Overlapping homologous superfamilies

Family relationships


MOCS2A is a the small subunit of the molybdopterin synthase complex that catalyses the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, MOCS2A serves as sulfur donor by being thiocarboxylated at its C terminus by UBA4 [PMID: 18491921]. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin [PMID: 10053004, PMID: 16737835].

GO terms

Biological Process

GO:0006777 Mo-molybdopterin cofactor biosynthetic process

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005829 cytosol

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.